50. Serious cause for refusing or leaving an employment or taking leave from an employment also exists if the adult has no reasonable alternative to refusing, leaving or taking leave, having regard to all the circumstances, including any of the following:(1) obligation to accompany a spouse or dependent child to another residence;
(2) working conditions that constitute a danger to health or safety;
(3) obligation to care for a child or a member of the immediate family;
(4) excessive overtime work or refusal to pay for overtime work;
(5) reasonable assurance of obtaining another employment in the immediate future;
(6) earnings insufficient in relation to the expenses entailed, particularly childcare and transportation expenses;
(7) inaccessibility of the workplace, particularly because of the distance or the lack of appropriate transportation;
(8) any other circumstance prescribed by regulation.